Silab has conducted new efficacy studies for Cicactyl [1], a natural active ingredient derived from carob gum (Ceratonia siliqua).
Cicactyl was developed to accelerate and improve skin healing. It targets four key processes involved in the proliferation phase of wound healing: granulation tissue formation, vascular network development, wound re-epithelialization, and inflammation reduction.
Aesthetic procedure by fractionated laser
The healing efficacy of Cicactyl was initially demonstrated through a clinical study conducted on a cohort of adult Caucasian subjects having undergone a mechanical aggression by strippings. In addition to this data, Silab has tested the efficacy of Cicactyl following treatments by fractionated non-ablative or ablative laser on two additional cohorts, which may cause the appearance of erythema, a deterioration of the barrier function, a dehydration of the skin or a deterioration of the surface of the skin in the zone of the wound.
According to Silab, along with an aesthetic procedure of rejuvenation by fractionated non-ablative laser, Cicactyl formulated at 1% leads to a significant recovery of the barrier function of more than 90% in only 48 hours of application, compared to only 63% with the placebo. In addition, the active ingredient significantly attenuates the cutaneous erythema following the aesthetic procedure, an effect observed in 92% of the volunteers.
For skin lesions resulting from fractional ablative laser procedures, Silab observed a favorable improvement in erythema in the area treated with Cicactyl. After just 24 hours of application, erythema was three times less severe than in the placebo-treated area. According to Silab, Cicactyl also promotes skin rehydration and improves the quality of skin repair following the procedure.
“All these results show that Cicactyl is an effective care product, is well tolerated and combines rapidity of action and efficacy in the care of wounded or damaged skin requiring repair,” said Silab in press release.
