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Ingredients & formulation

Seqens enhances self-image perception with new biotech ingredient

Seqens (formerly Novacap) is launching a series of innovations at in-cosmetics Paris 2019. With three new products presented at the annual event which opens its doors tomorrow, the France based supplier of speciality ingredients addresses several beauty trends: naturalness, skin microbiome, skin evenness and texture, skin moisturization.

Capitalizing on their expertise in biotechnology, Seqens has developed a high molecular weight polysaccharide rich in uronic acid. Produced by Alteromonas sp strain, Glycuron 2.78 is an exopolysaccharide able to interact with DC-sign lectin [1] and Rhamnose receptor, respectively involved in inflammation and dermo-epidermal regeneration. Clinical tests run on a 1% Glycuron 2.78 cream versus placebo showed statistically significant results after 28 days, on hydration and a trend in favour of the Glycuron 2.78 cream regarding skin evenness and texture.

Furthermore, Seqens has evaluate the emotional impact of Glycuron 2.78 versus placebo. The company used Spincontrol’s patented technique Emospin, which is based on prosody (voice loudness and frequency) measurement and verbatim analysis.

The study shows that Glycuron 2.78 cream is able to significantly enhance self-image perception (what would you say of yourself), and projected halo perception (what do you think others think about yourself). Placebo did not generate any significant change in prosody or verbatim.

Skin microbiome

At in-cosmetics Global, Seqens will also launch Megabiotic-44 a Pre and Postbiotics complex derived from Lactobacillus bulgaricus GLB44, a microorganism already used in the food industry. In the cosmetic version developed for topical use, micro-organisms have been inactivated while keeping their probiotically produced bactericide peptides.

In vitro tests have shown the ability of Megabiotic-44 to modulate both the skin microbiome and the strains targeted in the field of product preservation (Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Staphylococcus epidermidis, Propionibacterium acnes).

In addition, clinical tests have demonstrated that Megabiotic-44 introduced at 1% in a formulation is able to significantly reduce the number of visible pores together with pore size versus placebo after 28 days.

New emollient

Last but not least, Seqens is also adding ChemoxyCare 6 to their portfolio of functional ingrdients. ChemoxyCare 6 is a humectant and emollient which, according to Seqens, also shows very good preservative boosting properties while being odourless, colourless. Non-sensitizing, with light feel, ChemoxyCare 6 is especially adapted to Asian skins.



[1] dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin

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