To address the market demand for stable, easy-to formulate, highly bioavailable and well-tolerated vitamin A, Sederma is launching an encapsulated retinol. Indeed, while having demonstrated its benefits on wrinkles, stretch marks, skin blemishes and scars for decades, retinol is also known for some drawbacks, including possible skin irritation and chemical instability.
Dubbed ReVitAlide, the new ingredient is a lipid submicron particle carrying 3% active retinol. According to the Croda Personal Care subsidiary, this high-tech capsule provides enhanced stability, protecting retinol from degradation and making it easy to store and formulate.
“The small particle size and unique lipid composition of the capsule greatly improves bioavailability into the skin, with a controlled release process of the encapsulated retinol,” said Sederma in a statement.
Skin delivery of ReVitAlide measured on skin explants showed a 7-fold increase in the delivery of retinol into the skin versus non encapsulated retinol.
Protection of the active and enhanced delivery into the skin thus reinforce its efficacy and allow to minimise its use level, while offering excellent skin tolerance.
ReVitAlide is IECIC  compliant and is made of 95.50% natural content (according to ISO 16128). It is 100 % readily biodegradable in 28 days, RSPO approved and can be stored at room temperature.