Givaudan Active Beauty has unveiled PrimalHyal 50 Life, a new low molecular weight hyaluronic acid, the company claims to be “the most sustainable” in its portfolio [1]. Leveraging microbial strain engineering and precision fermentation, Givaudan Active Beauty said to have achieved an outstanding -91% reduction in environmental impact during the production process.

According to the company, PrimalHyal 50 Life boasts:
 a reduction of 92% in greenhouse gas emissions;
 a reduction of 95% in acidification and eutrophication of water;
 a reduction of 90% in non-renewable energy usage;
 a reduction of 75% in water consumption.

Unveiled at the Cosmet’agora trade exhibition in Paris, France, on 16-17 January 2024, PrimalHyal 50 Life bestows several skincare benefits, including: deep skin penetration, up to 120 μm, stimulation of tight junctions, preventing transepidermal water loss (TEWL) to boost skin hydration for up to 72 hours post-application, a reduction of skin roughness by -66% in 1 month, and perceivable benefits in terms of skin texture, firmness, and hydration, as noted by volunteers.

"Thanks to the outstanding work of our scientists in strain engineering, we have totally reinvented the production method for low molecular weight HA. By directly obtaining the molecular weight of interest during the fermentation stage, we have drastically reduced our global footprint. This is a breakthrough achievement for the beauty industry as a whole,” said Romain Reynaud, Research & Development Director at Givaudan Active Beauty.