Modern lifestyles are always more intense and have a real impact on the appearance of the skin. “Disturbed circadian rhythm, our inside clock, affects most of biological processes, leading to a tired skin and a bad mood,” explains Greentech.

To prevent these negative repercussions, Greentech has created Circalys, an active ingredient titrated in andrographolide, a molecule identified by the group’s scientists as able to counteract circadian disruption and revitalize skin.

Inspired by Ayurveda, Circalys was developed from Green Chiretta (Andrographis paniculata), a major detoxifying plant in Ayurvedic traditional medicine.

Circadian rhythm & brain axis modulator

According to Greentech, Circalys helps modulate skin rhythms, by restoring a “young” invigorating clock gene expression profile in old/tired skin cells and by acting on circadian modulators related to key cellular pathways. “It extends cell longevity, reduces cell damages, promoting skin revitalization. Circalys also stimulates key signaling pathways connecting skin and brain, also influenced by circadian clock. It boosts oxytocin, endocannabinoid and endorphin signaling pathways to relax and protect skin from modern life impacts.

Clinically tested on night/shift workers

Greentech has tested the efficacy of the new ingredient on night/shift workers in a double-blind clinical study. According to the company, the use of Circalys during 28 days led to a significant reduction of visible signs of fatigue : eye bags, dark circles and under-eye wrinkles. Volunteers also found their skin more radiant, comfortable and rested.

In addition, with the help of three “scientifically recognized” psychological tests, Greentech has also shown that the use of Circalys in a cosmetic formula also significantly modulated the impacts of fatigue on mood : boosted feeling of well-being, reduced perceived stress and negative affect («yoga-like» effect).

Emotional cosmetics

The development of this new active is part of the psychobiological approach implemented by Greentech in connection with the growing expectations of consumers in terms of well-being.

An increasing number of scientific studies established a bidirectional link between skin/hair aspect or disorders and the psychological state of people. Skin and hair are the most noticeable parts of our body and thus important for self-image and mental health,” explains the French manufacturer of natural active ingredients. “Skin has revealed itself to be a complex organ involved in multiple neuro-immuno-endocrine functions, connecting skin and brain, and involved in many skin and hair functions.

Today, four Greentech active ingredients are based on this systemic approach, addressing different skin and hair issues, supported by articles published in international scientific journals:

- Circalys, to counteract the impacts on skin and mood of fatigue and modern lifestyles;
- Hebelys, to address skin and emotional need of the silver generation woman with Positive Aging.
- Expozen, to sooth visible and perceived signs of skin sensitivity.
- Arcolys, to restore natural hair colour and boost self-esteem.