Backed by new studies, Seppic highlights Aquaxyl’s beneficial effects on the skin’s biological balance. These findings complement the iconic ingredient’s already well-established action on the skin barrier.
Dual biological action
A series of in vitro investigations have highlighted Aquaxyl’s dual biological action on the microbiome.
On the one hand, Aquaxyl exerts a selective prebiotic action. From 1.5%, the active ingredient significantly stimulates the growth of beneficial commensal bacteria such as Staphylococcus epidermidis (+28%) and Corynebacterium xerosis (+25%), that play a key role in maintaining a healthy barrier.
On the other hand, at 3%, Aquaxyl demonstrated inhibitory activity against pathogenic biofilms in a reconstructed human epidermis model. The data reveals a 59% reduction in biofilm formation by Staphylococcus aureus. “By limiting the adhesion and colonization of these opportunistic micro-organisms, Aquaxyl helps prevent dysbiosis and protects skin balance,” said Seppic.
A star ingredient reveals new potential
Powered by its patented sugar complex (Xylitylglucoside - Anhydroxylitol - Xylitol), Aquaxyl has established itself as a leading skin hydration ingredient. According to Seppic, over 2,500 global brands worldwide have adopted it over the past five years. This ingredient stands out for its universality and tolerance, proven across a wide range of phototypes.
By demonstrating Aquaxyl’s ability to support the skin’s biological balance, thus complementing its recognized action on the skin barrier with a global homeostasis approach, Seppic opens new possibilities for this ingredient.
With consumers becoming more aware of the crucial role played by the skin microbiome, the microbiome-focused skincare market — estimated at around USD 438 million in 2024 — is projected to grow to USD 1.4 billion by 2034 [1].
“The skin microbiome is the guardian of barrier function, innate immunity, and protection against pathogens. A balanced ecosystem is essential for normal skin function, while an imbalance of this flora is today identified as the source of many skin disorders,” highlighted Seppic.
