The extract obtained from leaves of Centella asiatica and titrated in triterpenes (madecassoside and asiaticoside) was found new properties by acting not only at the cellular but also structural level. Indeed, the last objectification test performed on human keratinocytes showed an increase in the synthesis of ceramides 2 thus improving the skin’s barrier and permeability. In addition, previous data showed the active to normalize keratinocyte differentiation through its action on the involucrin synthesis. Its interest also lies in the strengthening of tight junctions ensuring a greater cell cohesion and activation of the deep epidermis layers through aquaporins 3 stimulation.
Its broad potential of action on the skin barrier function combined with a modulation of inflammatory drifts (IL-1, IL-8, PGE-2) enables to recommend it for sensitive and reactive skins but also as an anti-ageing active.
Bayer Serdex is a division of Bayer Santé Familiale owned by the German group Bayer. It has been involved since the 70s in research and innovation work focusing on the activity of Malagasy plants intended for pharmaceutical and cosmetic applications. The division takes a careful attention to strictly implement the principles of ethical sourcing.