The update features six new restrictive Standards based on Quantitative Risk Assessment (QRA) and one new Standard prohibiting the use of 2,4-Octadienal.
IFRA has also withdrawn the Standard for Vanillin, which was first put in place with the 44th Amendment. This Standard was put on hold on 1st December, 2009, has now been officially withdrawn. Following the Vanillin Standard’s notification additional information was submitted, which allowed for a re-evaluation of the material. “After further additional testing and a critical evaluation of all available data today, IFRA has decided to withdraw the Standard and not set a revised Standard,” said the association in a release.
IFRA has also updated various guidance documents as part of the 46th Amendment.
- QRA Information Booklet Version 6.0 Final 2011 (including guidance on classes for IFRA Certificates)
- Annex 1 to the IFRA Standards which has been updated with contributions from other sources for o-Methoxycinnamaldehyde and Safranal
- Index (list of all IFRA Standards)
- Standard Operating Procedures (SOP) for the implementation of IFRA Standards
All the new Standards and related guidance documents are freely available on the IFRA website: www.ifraorg.org
1. Six new Standards, based on the QRA
2. One new Standard prohibiting the use of 2,4-Octadienal
2,4-Octadienal has been reviewed by the RIFM Expert Panel and, due to lack of adequate data (Dermal DNA Adduct study), it was concluded that it should not be used as or in fragrance ingredients in whatever application until additional data is available and considered sufficient to support its use. The presence of a structural alert as defined in the Human Health Criteria Document justifies this ban which already concerns several materials of the same structural family.